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Subject: phytic acid/Hiv
[Inhibitory effect of inositol hexasulfate and inositol hexaphosphoric
acid (phytic acid) on the proliferation of the human immunodeficiency
virus (HIV) in vitro]
Kansenshogaku Zasshi. 1989 Jul;63(7):676-83. Unique Identifier :
AIDSLINE MED/90131940
Otake T; Shimonaka H; Kanai M; Miyano K; Ueba N; Kunita N; Kurimura T
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Abstract: The monosaccharide substances inositol hexasulfate (IHS) and
inositol hexaphosphoric acid (Phytic acid, IHP) were investigated for
their antiviral effect on the human immunodeficiency virus (HIV) in
vitro. In MT-4 cells IHS completely inhibited the cytopathic effect of
HIV and the HIV specific antigen expression at a concentration of 1.67
mg/ml. IHP moderately inhibited both of HIV effects as mentioned
above.
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Keywords: *Antiviral Agents English Abstract Human HIV/*DRUG
EFFECTS/GROWTH & DEVELOPMENT HTLV-I Infections/PATHOLOGY
Inositol/*ANALOGS & DERIVATIVES/PHARMACOLOGY Monocytes/DRUG
EFFECTS/MICROBIOLOGY Phytic Acid/*PHARMACOLOGY JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).
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