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Subject: cupping/trigeminal neuralgia

   
   J Tradit Chin Med 1997 Dec;17(4):272-4
   
Observation on therapeutic effects of blood-letting puncture with cupping in
acute trigeminal neuralgia.

    Zhang Z
    
   Tianjin Municipal Hospital of Traditional Chinese Medicine.
   
   In the present paper, 45 cases of acute trigeminal neuralgia were
   treated and observed by comparative method. Results showed no
   significant difference in transient analgesic effect (P > 0.05) but a
   significant difference in therapeutic effect (P < 0.01) between the
   treatment and control groups. This indicates that blood-letting
   puncture with cupping is an effective therapy for the disease.
   
   Publication Types:
     * Clinical trial
     * Randomized controlled trial
       
   PMID: 10437209, UI: 99366262
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I suppose if one were to look at this article and then remember
that sickle cell patients begin to have their crisis WHEN their
iron levels rise .. one 'could' go .. hmmm..
   
First do no harm ..

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   Neurology 1980 Feb;30(2):210-1
   
Multiple cranial neuropathies, trigeminal neuralgia, and vascular headaches in
sickle cell disease, a possible common mechanism.

    Asher SW
    
   Patients with sickle cell disease are subject to a variety of
   neurologic complications. A patient with sickle cell disease and
   rarely noted features or complications is described. The association
   of abnormal (sickle-type) hemoglobin (Hgb S) with trigeminal and
   facial neuropathies and vascular headaches appeared to coincide with
   reactivation of the hematologic disease.
   
   PMID: 6243763, UI: 80121063
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Subject: sickle cell

   
   Arch Pediatr 2000 Mar;7(3):249-55
   
[Prevention of sickle cell crises with multiple phlebotomies].

   [Article in French]
   
    Bouchair N, Manigne P, Kanfer A, Raphalen P, de Montalembert M, Hagege I,
    Verschuur A, Maier-Redelsperger M, Girot R
    
   Service de pediatrie, CHU, Constantine, Algerie.
   
   OBJECTIVES: Sickle cell disease patients suffering from frequent
   painful crises were submitted to phlebotomies in order to reduce
   hospitalization days due to pain, through hemoglobin (Hb) level
   reduction and iron deficiency in patients with an hemoglobin level
   equal to or above 9.5 g/dL. PATIENTS: Seven sickle cell disease
   patients (four SC, three SS), aged four to 24 years, were submitted to
   sequential phlebotomies during periods from 18 months to four years.
   METHODS: The number of hospitalization days for crises was considered.
   The volumes and frequencies of phlebotomies were adjusted according to
   the patients ages, the hemoglobin concentrations and the serum
   ferritin levels. RESULTS: One hundred and forty-four hospitalization
   days were recorded in the seven patients in the year preceding the
   treatment. During the study period, the annual numbers of
   hospitalization days were respectively 20, five, six and one. Mean
   hemoglobin concentration was 10.7 g/dL before phlebotomies and 8.8 to
   9.2 g/dL during the four years of treatment. Mean corpuscular volume,
   mean corpuscular hemoglobin concentration and serum ferritin were also
   reduced. The volume of phlebotomies was 116 to 39 mL/kg/year according
   to the patients. COMMENTS AND CONCLUSION: The striking decrease of the
   number of hospitalization days for all the patients suggests a closed
   relationship between therapy and clinical improvement. The mechanism
   of this effect is probably multifactorial: a) the concentration of Hb
   level is known to influence the blood viscosity and its decrease
   always improved rheology in sickle cell disease patients; b) the mean
   corpuscular hemoglobin concentration is a critical factor concerning
   the HbS molecule polymerization in sickle cell disease, and its slight
   reduction may have an important biological effect. We observed these
   two biological modifications in our patients and suggest that they
   mediate the clinical effects. The iron deficiency induced by
   phlebotomies has no evident deleterious consequence either on height
   and weight in the children or on intellectual performance in any
   patients.
   
   Publication Types:
     * Clinical trial
       
   PMID: 10761600, UI: 20224666
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